Tissue optical clearing is a fundamental technique that enhances light penetration deep into biological samples by reducing light scattering through refractive index homogenization. This process ...

Steps for deep-tissue 3D-imaging. Embryos or neonates fixed with 4% PFA were optically cleared with 60% TDE or tissue-clearing reagent CUBIC-L/R, and imaged using stereoscopic, confocal, or two-photon ...

“I tested it three or four times before I believed it,” said Shigenori Inagaki of the discovery that enabled the breakthrough ...

It is now possible to obtain three-dimensional, high-resolution images of enzyme activity in tissue samples or whole organs -- thanks to probe molecules that anchor fluorescent dyes within tissue as ...

Scientists at the University of Warwick and University of Exeter have developed a fully fiber-coupled terahertz (THz) imaging ...

Scientists at Kyushu University made living mouse brains transparent using blood protein, revealing firing neurons without ...

Researchers at Niigata University have used advanced three-dimensional (3D) imaging to reveal how amyloid β (Aβ) deposits spread along blood vessels in the human brain in cerebral amyloid angiopathy ...