Modifications made during metabolic engineering for overproduction of chemicals have network-wide effects on cellular function due to ubiquitous metabolic interactions. These interactions, that make ...

Orthogonality is a concept often used to describe modular and maintainable software, but it’s more easily understood by way of a case study. In this article, Jens Dietrich demystifies orthogonality ...

Simply put, orthogonal validation uses additional methods that provide very different selectivity to the primary method to confirm or refute a finding. All methods are independent approaches that can ...

In mathematical circles, the word ‘orthogonal’ is used to define relations or objects that are non-overlapping, uncorrelated or independent. This definition is highly relevant when referring to ...