Addressing overdoses from “street drugs” containing potent synthetic opioids poses a key challenge when utilizing opioid antagonists. A standard approach to known or suspected opioid overdose includes ...

New research led by UCLA Health has found a drug that treats insomnia works to prevent the addictive effects of the morphine opioids in mice while still providing effective pain relief. At high doses ...

Scientists have known for decades that opioids relieve pain by binding to molecular switches in the brain called mu-opioid (pronounced "mew-opioid") receptors. What they didn't know - until now - was ...

Mood and anxiety disorders are leading causes of disability worldwide and are major contributors to the global burden of diseases. Neuropeptides, such as oxytocin and opioid peptides, are important ...

Pruritus is a well-recognized adverse effect of systemic opioids. While not typically life-threatening, pruritus may have an impact on patient comfort, quality of life, and willingness to continue ...

Employing a nurse care manager to work with patients who have an opioid addiction and prescribing partial or full opioid agonists can help more people enter treatment in primary care settings, ...

People taking GLP-1 receptor agonists such as semaglutide for diabetes or obesity showed lower rates of new alcohol and ...

Drugs that target opioid receptors sometimes have severe side effects. Thousands of people around the world die every day from overdoses involving opioids such as fentanyl. Researchers have taken a ...

The decision allows paramedics to start treatment during 911 calls for the first time and link patients with ongoing support.