The Human Genome Project changed everything. A map of the entire human sequence of DNA was the starting point for an enormous number of discoveries, from disease genes to how humans evolved. But DNA ...

In its effort to correlate genomic structure with gene function, the 4D Nucleome Consortium (4DN), led by Job Dekker, Ph.D., ...

Scientists created the largest functional map of a brain to date using a piece of a mouse's brain. The map details the wiring that connects neurons, offering insight into brain function and ...

An illustration of multicolored tangle of threads within a small black sphere. A 3D illustration shows DNA packaged into the nucleus, scientists with the 4D Nucleome project are now building accurate ...

In a landmark effort to understand how the physical structure of our DNA influences human biology, Northwestern investigators and the 4D Nucleome Project have unveiled the most detailed maps to date ...

NIH funding has allowed scientists to see the DNA blueprints of human life—completely. In 2022, the Telomere-to-Telomere Consortium, a group of NIH-funded scientists from research institutions around ...

The ability to sequence and edit human DNA has revolutionized biomedicine. Now a new consortium wants to take the next step and build human genomes from scratch. The Human Genome Project was one of ...

The Human Genome Project was supposed to unlock all of life’s secrets. Once we had a genetic roadmap, we’d be able to pinpoint why we got ill and figure out how to fix our maladies. That didn’t pan ...

J. Craig Venter, PhD, left, President Bill Clinton, and Francis S. Collins, MD, PhD, The White House, June 26, 2000. [Mark Wilson/Newsmakers/Getty Images] The announcement of the first draft of the ...

A new study challenges what's long been assumed about genetic variants thought to always cause inherited blindness.