Chronic rhinosinusitis with nasal polyps (CRSwNP) represents a persistent inflammatory disorder of the nasal mucosa and paranasal sinuses, often typified by type 2 immune polarisation, eosinophilic ...

B-ALL is the most common pediatric cancer and, over the years and thanks to a very effective treatment based on glucocorticoids, its 5-year survival rates have reached 85% and beyond. However, there ...

Since the start of the COVID-19 pandemic, a class of corticosteroids called glucocorticoids (GCs) has become established as one of the main treatment options, especially for severe cases, thanks to ...

Cortisone and other related glucocorticoids are extremely effective at curbing excessive immune reactions. But previously, astonishingly little was known about how they exactly do that. Researchers ...

More than 44% of individuals receiving high doses of prolonged glucocorticoid medication develop osteonecrosis, with the femoral head being the most commonly affected site, predominantly in those aged ...

Josep Carreras Leukaemia Research Institute B-ALL is the most common paediatric cancer and, over the years and thanks to a very effective treatment based on glucocorticoids, its 5-year survival rates ...

Drugs to treat inflammatory and autoimmune diseases - such as asthma, psoriasis, rheumatoid arthritis or Chrousos syndrome - act mainly through the glucocorticoid receptor (GR). This essential protein ...

Used clinically since the 1920s, corticosteroids interrupt multiple steps in immune activation because of the ubiquitous expression of corticosteroid receptors. Corticosteroids inhibit antigen ...

Taking glucocorticoids such as prednisone may increase your risk of developing glucocorticoid-induced osteoporosis. Diet and exercise decrease your risk, but some people may also need to reduce their ...