Same cuts, different responses Gene editing uses a protein called Cas9 as molecular scissors to cut targeted DNA and change its sequence. In the new study, the scientists discovered that gene editing ...

New research dramatically expands the number of naturally occurring versions of CRISPR-associated transposons (CASTs), giving researchers a wealth of potential new tools for large-scale gene editing.

The 2012 landmark Science paper demonstrating the use of CRISPR-Cas9 as a gene-editing tool catapulted gene-editing technologies to new levels. Yet, that breakthrough also highlighted precision and ...

Artificial intelligence (AI) is known for enabling deeper insights into drug development, identifying patterns and molecules that may otherwise go unnoticed. Now it is poised to make similar ...

A new gene-editing technique enables the correction of multiple genetic mutations simultaneously, transforming the prospects for millions living with complex inherited diseases, such as cystic ...

A schematic showing the cytosine base editing intermediate and the various outcomes that can occur when the UNG protein is active. You may have seen it in the news recently: a baby in Pennsylvania ...

In recent years, non-viral methods for cell engineering have emerged as promising alternatives to viral transduction. Amongst the virus-free technologies, electroporation is considered the gold ...

In a cutting-edge medical experiment, a small group of people who had high cholesterol despite taking conventional drugs to lower it saw significant reductions in two major risk factors for heart ...

In the late 2010s eight macaque monkeys were born at a laboratory in Shanghai. At first they seemed much like the other infants in the colony, but differences soon became obvious. They were much more ...

Australian cancer researchers are the first to establish a next-generation gene-editing tool for modeling and interrogating human disease. A novel pre-clinical model expressing an enhanced version of ...