The identification of evolutionarily constrained sequences is an unbiased approach for finding functional sequences in genomes. However, their identification is strongly affected by upstream analyses.

With the availability of genome sequences for an increasing number of metazoan organisms, the data are now present to carry out large-scale comparative genomic studies. The size of sequenced metazoan ...

In recent years, there has been growing discussion about digital public infrastructure (DPI)—systems such as digital identity systems, alternative payment methods, and data exchanges that are backed ...

In the article that accompanies this editorial, Lu et al 5 conducted a systematic review on the use of instrumental variable (IV) methods in oncology comparative effectiveness research. The main ...

Comparative effectiveness research increasingly is being recognized as a priority area in cancer research. Although researchers have been conducting comparative effectiveness research for decades, ...

Within the prior 24 months, I have had a financial relationship with a company producing, marketing, selling, re-selling, or distributing healthcare products used by or on patients: Receive the the ...