Cell signalling pathways are central to maintaining cellular homeostasis and regulating essential functions such as proliferation, apoptosis, and repair. In both cancer and neurodegenerative diseases, ...

In certain contexts, the Notch receptor may participate in “reverse signaling,” influencing neighboring cells directly.

Autophagy is essentially the 'rubbish collection' of our cells. If there are problems in this process, which is so important for our health, diseases such as Parkinson's can result. In their latest ...

A team at Huntsman Cancer Institute at the University of Utah (the U) has uncovered a previously unrecognized molecular ...

Sepsis is a complex clinical syndrome characterized by dysregulated immune responses, systemic inflammation, and multi-organ dysfunction. It involves intricate interactions among multiple signaling ...

The researchers used lipid nanoparticles (LNPs) to deliver cyclic GMP-AMP (cGAMP) synthase (cGAS) mRNA to cancer cells. This results in production of the endogenous stimulator of interferon genes ...

Initially, cells are dissociated from liver tissues into single-cell suspensions using in vivo enzymatic perfusion or ex vivo digestion methods. The cells of interest are then enriched from the ...

Objective B-cell activating factor (BAFF) is essential for B-cell survival and innate immune activation, and its ...

Cancer cells that accumulate extra copies of their entire chromosome set can start behaving like immune cells, swallowing their neighbors and migrating through tissue to seed tumors in distant organs.

Ways to Support Memory, Focus, and Brain Vitality Springville, United States - May 14, 2026 / SISEL International, ...