How major nuclear protein complexes control specialized gene regulation in cancer and beyond

Precision and timing of gene expression is essential for normal biological functions and, when disrupted, can lead to many ...
Ophthalmology Times

First patient treated in dose-expansion portion of SpliceBio's phase 1/2 ASTRA clinical trial

SpliceBio has dosed the first patient in the Part B dose-expansion portion of its phase 1/2 ASTRA clinical trial ( ...
GEN

Gene Syntax Guidelines to Increase Expression and Predictability

Sizeable differences in gene expression means and ratios—based solely upon where genes are located on a plasmid (gene syntax)—have been discovered by researchers at Dartmouth College. This new ...

Chromatin Bioscience, Mediphage Bioceuticals, and Entos Pharmaceuticals, collaborate on Genetic Medicines Project with support from UKRI Innovate UK and …

Chromatin Bioscience, Mediphage Bioceuticals, and Entos Pharmaceuticals are pleased to announce they are receiving advisory ...
PharmTech

Genetic Medicines Project Gets Funding from UKRI Innovate UK and Canadian NRC IRAP

UKRI Innovate UK and NRC IRAP provide funding and advisory support, fostering UK-Canada collaboration in genetic medicine ...
BioTechniques

Key cellular complex plays unexpected role in gene expression

Research has uncovered a previously unknown, widespread role of ORC in regulating human cell gene expression. New work has revealed a much wider role for origin-recognition complex (ORC) in regulating ...
Morningstar

MavriX Bio Announces First Patient Dosed in ASCEND-AS Trial of MVX-220, Investigational Gene Therapy for Angelman Syndrome

MIDDLETON, Mass., Nov. 6, 2025 /PRNewswire/ -- MavriX Bio, a clinical-stage biotechnology company focused on the development of transformative genetic therapies for Angelman syndrome (AS), today ...